Notify sufferers that a house teaspoon just isn't an accurate measuring system and this kind of use could lead to overdosage and really serious adverse reactions [see OVERDOSAGE (10)]. For prescriptions where by a measuring machine is not offered, a pharmacist can provide an acceptable calibrated measuring unit and can offer Guidelines for measuring the right dose.
On account of inconsistencies concerning the drug labels on DailyMed along with the pill images supplied by RxImage, we no longer Show the RxImage pill pictures linked to drug labels.
Should the response to an opioid antagonist is suboptimal or only brief in nature, administer additional antagonist as directed through the product or service's prescribing data. The respiratory depressant results of promethazine aren't reversed by opioid antagonists, like naloxone. As a result of prospective for promethazine to reverse epinephrine's vasopressor impact, epinephrine should NOT be utilized to deal with hypotension linked to promethazine overdose.
In determining to implement a medication, the hazards of getting the medicine have to be weighed versus The great it'll do. This is often a decision you and your health practitioner could make. For this medication, the subsequent ought to be considered:
This merchandise may perhaps have inactive elements, that may cause allergic reactions or other problems. Discuss with your pharmacist For additional aspects.
Hold an index of all the products and solutions you utilize (like prescription/nonprescription medication and herbal merchandise) and share it together with your health care provider and pharmacist. Never get started, quit, Promethazine codeine syrup or change the dosage of any medicines without your medical doctor's acceptance.
Get medical assistance instantly when you notice any of the subsequent: sluggish/shallow breathing, intense drowsiness/trouble waking up, confusion.
Endocrine/Metabolic: Scenarios of serotonin syndrome, a potentially existence-threatening affliction, have already been claimed throughout concomitant use of opioids with serotonergic medication.
These signs and symptoms may possibly indicate that you're an "extremely-quick metabolizer of codeine". Due to this fact, there is too much morphine in your body and more Unwanted effects of morphine than standard. Youngsters may very well be In particular sensitive to this impact. Never give this medicine to:
This individual populace is presumed to possess a background of challenges linked to material misuse/abuse, injection drug use, and chronic pain. These patterns suggest that, in accidental deaths, any variety of tactics are getting used by clients who engage in codeine misuse, which includes supplementing codeine with prescribed pain medication, persistently escalating dosages with no clinician acceptance, and offering/obtaining the drug beyond regulatory control.
Any professional medical information and facts published on this Web page isn't meant in its place for informed medical advice and you shouldn't just take any motion ahead of consulting using a healthcare Qualified. See added information.
Codeine has reduced plasma protein binding with about seven to 25% of codeine certain to plasma proteins. Codeine passes the blood Mind barrier along with the placental barrier. Modest amounts of codeine and its metabolite, morphine, are transferred to human breast milk.
This information will take a look at what opioids are, the differing types of opioids, and the way to get aid for dependancy or overdose.
Promethazine with Codeine Oral Answer just isn't encouraged for use in pregnant Girls. Prolonged utilization of Promethazine with Codeine Oral Answer in the course of pregnancy may lead to withdrawal during the neonate. Neonatal opioid withdrawal syndrome, not like opioid withdrawal syndrome in Grown ups, may be everyday living-threatening if not acknowledged and addressed, and involves management Based on protocols created by neonatology experts.